A stack is more
than a list.
A supplement stack audit examines chemical form, elemental amount, duration and documented nutrient relationships. This browser tool checks twelve selectable compounds against a defined set of source-linked rules. It distinguishes nicotinic acid from nicotinamide and historical hypotheses from established nutrient interactions. An unflagged selection is not complete interaction clearance or proof of safety.
NIH Office of Dietary Supplements, Zinc — Health Professional Fact Sheet NIH Office of Dietary Supplements, Niacin — Health Professional Fact Sheet
01 / YOUR INPUTS
What is in the stack?
Chemical form matters; this field is for nicotinic acid.
Your entries stay in this browser. They are not attached to waitlist submissions. Download or copy a scorecard only when you choose.
02 / THE COMPARISON
The number,
with its context.
Enter or select the information on the left to see a source-labeled comparison.
The result will retain the units, source and limits relevant to this comparison.
A DEFINED RULE SET
The flag should
show its work.
Start with the chemical form.
Nicotinic acid and nicotinamide are distinct forms of vitamin B3. Selecting a “non-flush” label does not establish equivalence or safety. The audit keeps those entries separate and uses an optional nicotinic-acid amount for exposure context.
Read zinc exposure with copper context.
The NIH zinc review notes that supplemental zinc at 50 mg/day or more for weeks can impair copper absorption. The rule asks about elemental amount and duration. Selecting copper does not automatically resolve the concern or define a supplement dosing ratio.
Distinguish evidence from a proposed pairing.
Garg and colleagues reported higher homocysteine in a randomized high-dose-niacin subgroup. McCarty’s betaine proposal is a Medical Hypotheses paper. The auditor surfaces that distinction without making TMG, folate or B12 a universal instruction.
Keep historical combinations historical.
Ascorbate and lysine appear in the Pauling–Rath literature; proline appears in Rath’s separate 1992 proposal. Identifying that combination is not proof of clinical benefit. This defined rule set is not a comprehensive interaction database.
READ THE ORIGINALS
Sources, within reach.
- NIH Office of Dietary Supplements, Zinc — Health Professional Fact SheetOfficial nutrient evidence summary
- NIH Office of Dietary Supplements, Niacin — Health Professional Fact SheetOfficial nutrient evidence summary; distinguishes nicotinic acid and nicotinamide
- Garg et al., 1999, American Heart Journal 138:1082–1087Randomized placebo-controlled ADMIT subgroup of52 participants with peripheral arterial disease
- McCarty, 2000, Medical Hypotheses 55:189–194Explicit hypothesis for betaine co-administration; not a clinical pairing rule
- Rath, 1992, Journal of Orthomolecular Medicine 7:153–162Separate proposed cardiovascular nutritional mechanism; not proof that a combination reverses disease
§ 06 EARLY ACCESS
"In normal range" was
never really an answer.
Join the early-access waitlist and get instant access to our Orthomolecular Optimal vs. Standard Lab Reference Sheet.
You're on the list.
Your lab reference sheet is ready: ten markers, assay-specific ranges, primary sources and the limits of proposed optimal targets.
Download the reference sheet ↓STEP 01 / HELP SHAPE THE APP