Ferritin, iron stores and inflammation: reading the reference interval

Ferritin can provide information about iron stores, but inflammation and clinical context affect interpretation. A normal-range label is only one part of that picture.

SOURCES CHECKED / 2026-11-04 · Educational reference

Check age and sex before comparing intervals

Both Quest and Labcorp separate ferritin intervals by age and sex. Labcorp updated its assay page in October 2026 and uses several adult female age bands. An undated graphic containing one universal ferritin interval can therefore misrepresent the laboratory report it is meant to explain. [1] [2]

Distinguish a reference interval from a decision threshold

WHO guidance discusses ferritin in the assessment of iron status and the influence of inflammation. Reference populations, deficiency thresholds and treatment goals are different concepts. A result needs to be interpreted in the context for which a threshold was developed. [3]

Read iron studies together

Ferritin is also an acute-phase reactant. A clinician may consider evidence of inflammation and other iron-related measurements rather than interpreting ferritin alone. A value inside a printed interval does not answer every question about iron status, and a higher result is not automatically a better one. [3]

Keep the clinical question explicit

Store the reason for testing, the exact assay interval and relevant related results with the value. Our source review did not identify a universal Pfeiffer, Walsh or Hoffer ferritin optimum. Use source-specific interpretation rather than treating a marketing target as an established treatment goal. [1] [2] [3]

Assay examples verified 2026-11-04. Refer to the interval on your own report.
MarkerQuest exampleLabcorp example
FerritinMen 19–59: 38–380; women 19–40: 16–154 ng/mL. Assay source ↗Men ≥20: 30–400; women 20–40: 30–150 ng/mL. Assay source ↗

These notes explain sources and testing context. They do not diagnose a condition, select a personal supplement dose or replace professional medical advice.

Sources worth opening.

  1. Quest ferritin assay 457 ↗
  2. Labcorp ferritin assay 004598 ↗
  3. WHO guideline on ferritin and iron status ↗

Your labs. Your stack.
The source beside the answer.

The following is an illustrative app preview. Proposed ranges shown in a product example are not universal diagnostic cutoffs.

LABS / OPTIMAL VS. NORMAL

Uploaded panel · Serum Ascorbate & Homocysteine

Serum Vitamin C

0.6 mg/dL

In Lab Normal, Below Optimal

Standard Lab Range
0.4 – 2.0 mg/dL
Orthomolecular Optimal
1.5 – 2.5+ mg/dL (tissue saturation)

Homocysteine

11.4 µmol/L

In Lab Normal, Elevated Methylation Load

Standard Lab Range
5.0 – 15.0 µmol/L
Orthomolecular Optimal
< 7.0 µmol/L [Pfeiffer / Walsh]
Reference ranges sourced from orthomolecular literature for educational comparison.
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